|
Clinical parameters in cough variant asthma patients with and without inhaled corticosteroids |
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| Without ICS |
With ICS |
P value |
Total |
|
|
|
||||
| Age (years) |
53.3 ± 14.3 |
47.6 ± 12.0 |
0.3495 |
49.9 ± 12.9 |
| Gender (male/female) |
2/6 |
5/7 |
0.4439 |
7/13 |
| Intreval of methcholine provocations (years) |
2.7 ± 1.0 |
3.4 ± 2.8 |
0.5172 |
3.1 ± 2.2 |
| 2.9 (1.1–4.0)* |
2.0 (0.5–8.0)* |
2.0 (0.5–8.0)* |
||
| Duration of illness (months) |
41.5 ± 51.9 |
23.6 ± 31.4 |
0.3466 |
30.8 ± 40.5 |
| 10.0 (2.0–120.0)* |
12.5 (2.0–108.0)* |
12.0 (2.0–120)* |
||
| Cough threshold (μM) |
11.1 (1.63)** |
6.2 (1.59)** |
0.4163 |
7.8 (1.40)** |
| PC20-FEV1 (mg/ml) |
2.13 (1.52) |
1.80 (1.35) |
0.7464 |
1.93 (1.27) |
| FVC (% predicted) |
105.4 ± 14.3 |
103.1 ± 19.1 |
0.7765 |
104.0 ± 17.0 |
| FEV1 (% predicted) |
97.4 ± 15.2 |
93.2 ± 16.4 |
0.5763 |
94.9 ± 15.7 |
| FEV1/FVC (%) |
73.3 ± 6.9 |
78.1 ± 6.5 |
0.1318 |
76.2 ± 6.9 |
|
*; median (range), **; geometric mean (geometric standard error of the mean). | ||||
Fujimura et al. Cough 2005 1:5 doi:10.1186/1745-9974-1-5 |
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