Table 1

Patient characteristics

Patient 1
 Patient 2
 Patient 3
 Patient 4
Age (years)
 52
 73
 46
 63
Gender (m/f)
 M
 F
 F
 M
Snoring
 Yes
 Yes
 Yes
 Yes
Nocturnal cough
 Yes
 Yes
 Yes
 Yes
Body mass Index (Kg/m2)
 35
 32
 37
 33
Baseline cough VAS
 90
 95
 50
 80
Post CPAP cough VAS
 0
 5
 0
 0
Cough duration at OSA diagnosis (mo)
 48
 6
 16
 8
FEV1 (%predicted)
 93
 61
 119
 100
FEV1/FVC (%)
 78
 70
 84
 83
PC20 mg/ml)
 >16
 nd
 >16
 >16
Sputum neutrophil (nr <65%)
 89
 -
 91
 87
Sputum eosinophil (nr <2%)
 0.3
 -
 1.4
 0.5
ESS preCPAP
 7
 14
 15
 15
ESS post CPAP
 3
 8
 7
 5
AHI baseline (per hour)
 36
 86
 62
 10 (4% SpO2 dips)
SpO2 (4% dips/hour) on CPAP
 0.7
 0
 3
 0
CPAP (cm H2o)
 12
 12
 8
 6
CPAP compliance (mean hours/night)
 6
 4
 7
 6

NR: normal range; VAS: visual analogue score (0–100 mm worst); CPAP: continuous positive airway pressure; OSA: obstructive sleep apnoea; FEV1: forced expiratory volume; FVC: forced vital capacity; PC20: provocative concentration of methacholine causing >20% decline in FEV1; ESS: daytime Epworth Sleepiness Scale (range 0–24, nr<11); AHI: apnoea hypopnoea index (nr< 5/hour); SpO2: oxygen saturation

Birring et al. Cough 2007 3:7   doi:10.1186/1745-9974-3-7