Table 3 |
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Over-the-counter and prescription medicines available for the therapy of acute cough |
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Type of product |
Component |
Available in combinations with |
OTC or prescription; formulation |
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Cough suppressant |
Benzonatate |
- |
Prescription; perles and capsules |
|
DXM polistirex |
- |
OTC; extended-release suspension |
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DXM |
Antihistamine: promethazine |
Prescription; syrup |
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|
Hydrocodone |
Agent to discourage overdose: homatropine |
Prescription; tablet and syrup |
|
|
Hydrocodone |
Antihistamine: chlorpheniramine |
Prescription; extended-release suspension and extended-release capsule |
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|
Antihistamine |
Brompheniramine |
- |
Prescription; elixir and injection |
|
Brompheniramine |
Cough suppressant + decongestant: DMX + pseudoephedrine |
Prescription; syrup |
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|
Chlorpheniramine |
Cough suppressant: codeine |
Prescription; extended-release suspension |
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Clemastine |
- |
OTC or prescription; tablet and syrup |
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Desloratadine |
- |
Prescription; tablet and syrup |
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Desloratadine |
Decongestant: pseudoephedrine |
Prescription; extended-release tablet |
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|
Dexbrompheniramine |
Decongestant: pseudoephedrine |
OTC; extended-release tablet |
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Dexbrompheniramine |
Decongestant + antipyretic: pseudoephedrine + acetaminophen |
OTC; extended-release tablet |
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Diphenhydramine |
- |
Prescription; injection, elixir and capsule |
|
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Loratadine |
- |
OTC; tablet and syrup |
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Loratadine |
Decongestant: pseudoephedrine |
OTC; extended-release tablet |
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Promethazine |
Cough suppressant: codeine |
Prescription; syrup |
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Promethazine |
Cough suppressant + decongestant: codeine + phenylephrine |
Prescription; syrup |
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Promethazine |
Cough suppressant + decongestant + antihistamine: codeine + phenylephrine + triprolidine |
Prescription; syrup |
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Expectorant |
Guaifenesin |
- |
OTC; tablet |
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Guaifenesin |
Cough suppressant: DXM |
OTC; tablet |
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Guaifenesin |
Decongestant: pseudoephedrine |
OTC; tablet |
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OTC = over-the-counter; DXM = dextromethorphan |
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Dicpinigaitis et al. Cough 2009 5:11 doi:10.1186/1745-9974-5-11 |
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