Table 3

Over-the-counter and prescription medicines available for the therapy of acute cough

Type of product

Component

Available in

combinations with

OTC or prescription; formulation


Cough suppressant

Benzonatate

-

Prescription; perles and capsules

DXM polistirex

-

OTC; extended-release suspension

DXM

Antihistamine: promethazine

Prescription; syrup

Hydrocodone

Agent to discourage overdose: homatropine

Prescription; tablet and syrup

Hydrocodone

Antihistamine: chlorpheniramine

Prescription; extended-release suspension and extended-release capsule

Antihistamine

Brompheniramine

-

Prescription; elixir and injection

Brompheniramine

Cough suppressant + decongestant:

DMX + pseudoephedrine

Prescription; syrup

Chlorpheniramine

Cough suppressant: codeine

Prescription; extended-release suspension

Clemastine

-

OTC or prescription; tablet and syrup

Desloratadine

-

Prescription; tablet and syrup

Desloratadine

Decongestant: pseudoephedrine

Prescription; extended-release tablet

Dexbrompheniramine

Decongestant: pseudoephedrine

OTC; extended-release tablet

Dexbrompheniramine

Decongestant + antipyretic: pseudoephedrine + acetaminophen

OTC; extended-release tablet

Diphenhydramine

-

Prescription; injection, elixir and capsule

Loratadine

-

OTC; tablet and syrup

Loratadine

Decongestant: pseudoephedrine

OTC; extended-release tablet

Promethazine

Cough suppressant: codeine

Prescription; syrup

Promethazine

Cough suppressant + decongestant:

codeine + phenylephrine

Prescription; syrup

Promethazine

Cough suppressant + decongestant + antihistamine: codeine + phenylephrine + triprolidine

Prescription; syrup

Expectorant

Guaifenesin

-

OTC; tablet

Guaifenesin

Cough suppressant: DXM

OTC; tablet

Guaifenesin

Decongestant: pseudoephedrine

OTC; tablet


OTC = over-the-counter; DXM = dextromethorphan

Dicpinigaitis et al. Cough 2009 5:11   doi:10.1186/1745-9974-5-11

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