Table 3

Capsaicin Cough Reflex Sensitivity Test, Urge-to-Cough and Leicester Cough Monitor Testing.

Measurement

Baseline

T1

T2

T3

T4

Post Treatment

P*

Log CRS, C5

μMol/L

0.88 ± 0.48

1.18 ± 0.62

1.46 ± 0.78

1.45 ± 0.68

1.53 ± 0.93

1.65 ± 0.88

< 0.0001

Cough Frequency

(coughs/hr)

72.5 ± 55.8

42.5 ± 60.5

63.0 ± 78.9

48.7 ± 36.8

29.4 ± 18.4

25.0 ± 27.9

0.009

Log Cough Threshold

μMol/L

0.47 ± 0.38

0.72 ± 0.60

0.80 ± 0.60

0.69 ± 0.23

0.66 ± 0.65

1.14 ± 0.76

0.001

Urge to Cough Score,

Median (IQR)

5 (1)

3.5 (4.0)

3 (5)

1.5 (3.0)

0.5 (1.0)

1 (4)

0.01

Mean ± SD unless otherwise indicated.

* Baseline vs Post Treatment T = Treatment Post = Post Treatment

Ryan et al. Cough 2010 6:5   doi:10.1186/1745-9974-6-5