Table 1 |
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|
Demographics, clinical data, and procedural observations for the study population and for groups by procedural posture. |
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|
All patients |
Supine |
Semi-recumbent |
p-value* |
|
|
|
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|
n |
69 |
33 |
36 |
|
|
|
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|
Age |
62 ± 14 |
64 ± 16 |
61 ± 13 |
NS |
|
Males (%) |
42 (61) |
19 (58) |
23 (64) |
NS |
|
Smoking status |
||||
|
- Current smokers (%) |
15 (22) |
9 (27) |
6 (17) |
NS |
|
- Ex-smokers (%) |
33 (48) |
16 (49) |
17 (47) |
NS |
|
- Non-smokers (%) |
21 (30) |
8 (24) |
13 (36) |
NS |
|
Inpatients (%) |
26 (38) |
11 (33) |
15 (42) |
NS |
|
Baseline SpO2 |
97.0 ± 2.2 |
96.9 ± 2.4 |
97.1 ± 1.9 |
NS |
|
Baseline pulse rate (/min) |
77 ± 13 |
76 ± 13 |
77 ± 13 |
NS |
|
% predicted FEV1 |
70 ± 19 |
67 ± 21 |
74 ± 17 |
NS |
|
% predicted FVC |
78 ± 17 |
79 ± 19 |
77 ± 14 |
NS |
|
Oral route (%) |
31 (45) |
15 (45) |
17 (47) |
NS |
|
Initial phase (min) |
3.7 ± 1.3 |
3.9 ± 1.5 |
3.6 ± 1.1 |
NS |
|
Cough rate (/min) |
4.8 ± 3.7 |
6.1 ± 4.5 |
3.6 ± 2.3 |
0.007 |
|
Sedative use |
||||
|
- Midazolam (mg) |
3.5 ± 1.7 |
4.0 ± 2.0 |
3.1 ± 1.2 |
0.029 |
|
- Fentanyl (mcg) |
79 ± 30 |
88 ± 28 |
70 ± 29 |
0.011 |
|
Nadir SpO2 |
93.4 ± 4.6 |
93.3 ± 4.3 |
93.6 ± 4.9 |
NS |
|
Fall in SpO2 |
3.6 ± 4.2 |
3.6 ± 3.6 |
3.6 ± 4.7 |
NS |
|
Peak pulse rate (/min) |
92 ± 16 |
91 ± 17 |
94 ± 15 |
NS |
|
Rise in pulse rate (/min) |
16 ± 13 |
16 ± 12 |
16 ± 14 |
NS |
|
Maximal O2 use (L/min) |
3.0 ± 1.8 |
3.0 ± 2.1 |
3.0 ± 1.5 |
NS |
|
Questionnaire† |
||||
|
- Nurse VAS discomfort |
31 ± 26 |
39 ± 28 |
23 ± 21 |
0.01 |
|
- Patient VAS recall |
49 ± 35 |
51 ± 35 |
47 ± 36 |
NS |
|
- Patient VAS discomfort |
24 ± 23 |
22 ± 23 |
27 ± 23 |
NS |
|
- Patient VAS cough |
33 ± 27 |
40 ± 28 |
28 ± 25 |
0.067 |
|
- Patient 1-4 repeat |
1.2 ± 0.4 |
1.2 ± 0.4 |
1.1 ± 0.4 |
NS |
|
|
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|
Values shown as mean ± SD or number (%). * p-values shown for comparisons between supine and semi-recumbent groups. † VAS responses measured in mm from the left end of the visual analogue scale. FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; SpO2, oxygen saturation; VAS, visual analogue scale; NS, not significant at > 0.05. |
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|
Ling et al. Cough 2011 7:9 doi:10.1186/1745-9974-7-9 |
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