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1:

Inhibition of citric acid- and capsaicin-induced cough by novel TRPV-1 antagonist, V112220, in guinea-pig.

Leung SY, Niimi A, Williams AS, Nath P, Blanc FX, Dinh QT, Chung KF.

Cough. 2007 Dec 23;3:10.

PMID: 18154688 [PubMed - in process]

2:

Inhibition of guinea-pig and human sensory nerve activity and the cough reflex in guinea-pigs by cannabinoid (CB2) receptor activation.

Patel HJ, Birrell MA, Crispino N, Hele DJ, Venkatesan P, Barnes PJ, Yacoub MH, Belvisi MG.

Br J Pharmacol. 2003 Sep;140(2):261-8. Epub 2003 Aug 4.

PMID: 12970104 [PubMed - indexed for MEDLINE]

3:

Animal models of cough: literature review and presentation of a novel cigarette smoke-enhanced cough model in the guinea-pig.

Lewis CA, Ambrose C, Banner K, Battram C, Butler K, Giddings J, Mok J, Nasra J, Winny C, Poll C.

Pulm Pharmacol Ther. 2007;20(4):325-33. Epub 2006 Dec 13.

PMID: 17240178 [PubMed - indexed for MEDLINE]

4:

Angiotensin-converting enzyme inhibitor and danazol increase sensitivity of cough reflex in female guinea pigs.

Ebihara T, Sekizawa K, Ohrui T, Nakazawa H, Sasaki H.

Am J Respir Crit Care Med. 1996 Feb;153(2):812-9.

PMID: 8564137 [PubMed - indexed for MEDLINE]

5:

Pharmacology and antitussive efficacy of 4-(3-trifluoromethyl-pyridin-2-yl)-piperazine-1-carboxylic acid (5-trifluoromethyl-pyridin-2-yl)-amide (JNJ17203212), a transient receptor potential vanilloid 1 antagonist in guinea pigs.

Bhattacharya A, Scott BP, Nasser N, Ao H, Maher MP, Dubin AE, Swanson DM, Shankley NP, Wickenden AD, Chaplan SR.

J Pharmacol Exp Ther. 2007 Nov;323(2):665-74. Epub 2007 Aug 9.

PMID: 17690251 [PubMed - indexed for MEDLINE]

6:

Capsazepine inhibits cough induced by capsaicin and citric acid but not by hypertonic saline in guinea pigs.

Lalloo UG, Fox AJ, Belvisi MG, Chung KF, Barnes PJ.

J Appl Physiol. 1995 Oct;79(4):1082-7.

PMID: 8567546 [PubMed - indexed for MEDLINE]

7:

TRPV1 antagonists attenuate antigen-provoked cough in ovalbumin sensitized guinea pigs.

McLeod RL, Fernandez X, Correll CC, Phelps TP, Jia Y, Wang X, Hey JA.

Cough. 2006 Dec 15;2:10.

PMID: 17173683 [PubMed]

8:

Involvement of P2X receptor subtypes in ATP-induced enhancement of the cough reflex sensitivity.

Kamei J, Takahashi Y, Yoshikawa Y, Saitoh A.

Eur J Pharmacol. 2005 Dec 28;528(1-3):158-61.

PMID: 16321375 [PubMed - indexed for MEDLINE]

9:

RSD931, a novel anti-tussive agent acting on airway sensory nerves.

Adcock JJ, Douglas GJ, Garabette M, Gascoigne M, Beatch G, Walker M, Page CP.

Br J Pharmacol. 2003 Feb;138(3):407-16.

PMID: 12569065 [PubMed - indexed for MEDLINE]

10:

Mechanisms of capsaicin- and citric-acid-induced cough reflexes in guinea pigs.

Tanaka M, Maruyama K.

J Pharmacol Sci. 2005 Sep;99(1):77-82. Epub 2005 Aug 26.

PMID: 16127241 [PubMed - indexed for MEDLINE]

11:

N-(4-tertiarybutylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: I. in vitro characterization and pharmacokinetic properties.

Valenzano KJ, Grant ER, Wu G, Hachicha M, Schmid L, Tafesse L, Sun Q, Rotshteyn Y, Francis J, Limberis J, Malik S, Whittemore ER, Hodges D.

J Pharmacol Exp Ther. 2003 Jul;306(1):377-86. Epub 2003 Apr 29.

PMID: 12721338 [PubMed - indexed for MEDLINE]

12:

A comparative study of the effects of citric acid, capsaicin and resiniferatoxin on the cough challenge in guinea-pig and man.

Laude EA, Higgins KS, Morice AH.

Pulm Pharmacol. 1993 Sep;6(3):171-5.

PMID: 8219571 [PubMed - indexed for MEDLINE]

13:

Studies on the magnitude and the mechanism of cough potentiation by angiotensin-converting enzyme inhibitors in guinea-pigs: involvement of bradykinin in the potentiation.

Takahama K, Araki T, Fuchikami J, Kohjimoto Y, Miyata T.

J Pharm Pharmacol. 1996 Oct;48(10):1027-33.

PMID: 8953504 [PubMed - indexed for MEDLINE]

14:

Effect of nociceptin in acid-evoked cough and airway sensory nerve activation in guinea pigs.

Lee MG, Undem BJ, Brown C, Carr MJ.

Am J Respir Crit Care Med. 2006 Feb 1;173(3):271-5. Epub 2005 Oct 20.

PMID: 16239621 [PubMed - indexed for MEDLINE]

15:

The effect of chemical stimulation of esophageal mucosa on citric acid induced cough and specific airway resistance in guinea pig.

Kollarik M, Plevkova J, Brozmanova M, Revallo M, Varechova S, Bartos V, Plank L, Tatar M.

Bratisl Lek Listy. 2005;106(3):101-6.

PMID: 16026143 [PubMed - indexed for MEDLINE]

16:

Synergistic interactions between airway afferent nerve subtypes regulating the cough reflex in guinea-pigs.

Mazzone SB, Mori N, Canning BJ.

J Physiol. 2005 Dec 1;569(Pt 2):559-73. Epub 2005 Jul 28.

PMID: 16051625 [PubMed - indexed for MEDLINE]

17:

Inhibitory activity of the novel CB2 receptor agonist, GW833972A, on guinea-pig and human sensory nerve function in the airways.

Belvisi MG, Patel HJ, Freund-Michel V, Hele DJ, Crispino N, Birrell MA.

Br J Pharmacol. 2008 Oct;155(4):547-57. Epub 2008 Aug 11.

PMID: 18695648 [PubMed - indexed for MEDLINE]

18:

[Sensitivity of the cough reflex in awake guinea pigs, rats and rabbits]

Tatár M, Pécová R, Karcolová D.

Bratisl Lek Listy. 1997 Oct;98(10):539-43. Slovak.

PMID: 9490169 [PubMed - indexed for MEDLINE]

19:

Antitussive and antibronchoconstriction actions of fenspiride in guinea-pigs.

Laude EA, Bee D, Crambes O, Howard P.

Eur Respir J. 1995 Oct;8(10):1699-704.

PMID: 8586125 [PubMed - indexed for MEDLINE]

20:

Cough and bronchoconstriction mediated by capsaicin-sensitive sensory neurons in the guinea-pig.

Forsberg K, Karlsson JA, Theodorsson E, Lundberg JM, Persson CG.

Pulm Pharmacol. 1988;1(1):33-9.

PMID: 2980286 [PubMed - indexed for MEDLINE]

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